Oxidative stress and male reproductive health

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Oxidative stress and male reproductive health

One of the major causes of defective sperm function is oxidative stress, which not only disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a result of collateral damage to proteins and lipids in the sperm plasma membrane. The origins of such oxidative stress appear to involve the sperm mitochondria, which have a tendency to generate high levels of su...

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Oxidative Stress on Male Reproductive Toxicity

Globally Harmonized System defines Reproductive Toxicity as “an adverse effects (of chemicals) on sexual function and fertility in adult males and females, as well as developmental toxicity in the offspring.” Several toxicity assessment studies have been performed taking into account the action of toxicants on reproductive activity. Testis is the main organ of male reproductive system and sperm...

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Oxidative stress & male infertility.

The male factor is considered a major contributory factor to infertility. Apart from the conventional causes for male infertility such as varicocoele, cryptorchidism, infections, obstructive lesions, cystic fibrosis, trauma, and tumours, a new and important cause has been identified: oxidative stress. Oxidative stress is a result of the imbalance between reactive oxygen species (ROS) and antiox...

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[Male sexual and reproductive health].

OBJECTIVE Analysing scientific publications about male sexual and reproductive health in Colombia during the last two decades and determining the main findings about knowledge regarding the topic in Colombia. METHODOLOGY A systematic review was made of scientific publications in international databases concerned with male sexual and reproductive health in Colombia. Inclusion criteria concerne...

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Oxidative stress and cytotoxic potential of anticholinesterase insecticide, malathion in reproductive toxicology of male adolescent mice after acute exposure

Objective(s):The present study was undertaken to determine the effects of acute exposure to malathion on oxidative stress and cytotoxic potential of anticholinesterase insecticide, malathion in reproductive toxicology of adolescent male mice. Materials and Methods: Thirty two adolescent male mice at pubertal age were treated with 500 mg/kg body weight (BW) of malathion for three days. After ex...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2014

ISSN: 1008-682X

DOI: 10.4103/1008-682x.122203